Co-founded by a
Dr. Molly Shoichet is internationally renowned for her innovative biomaterials and therapeutic delivery strategies. Shoichet addresses critical questions in medicine with her multidisciplinary research approach that spans drug discovery to drug delivery.
AmacaThera is strategically positioned to develop a pipeline of products that build on cutting-edge inventions in injectable hydrogels, formulation design, drug delivery, affinity release and cell therapy.
For more information about publications related to AmacaThera’s technology, please visit the Shoichet Lab.
2019A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system
Published in Brain Research Bulletin, Mar. 2019
2010Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury
Published in Biomaterials, Oct. 2010
2006Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord.
Published in Biomaterials, Jan. 2006
2020Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration
Published in Biomaterials, Oct. 2020
2019Initial cell maturity changes following transplantation in a hyaluronanbased hydrogel and impacts therapeutic success in the stroke-injured rodent brain
Published in Biomaterials, Feb. 2019
2019Controlled release strategy designed for intravitreal protein delivery to the retina.
Published in Journal of Controlled Release, Jan. 2019
2016Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles
Published in Science Advances, May 2016
2015A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation
Published in Stem Cell Reports, Jun. 2015
2013Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke.
Published in Journal of Controlled Release, Nov. 2013
2012Tunable growth factor delivery from injectable hydrogels for tissue engineering.
Published in Journal of the American Chemical Society, Jan. 2011
2012Hydrogel delivery of erthropoietin to the brain for endogenous stem cell stimulation after stroke injury.
Published in Biomaterials, Dec. 2011
2015Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.
Published in Journal of Controlled Release, Oct. 2015
2013A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.
Published in Journal of Controlled Release, Mar. 2013
2009Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel.
Published in Journal of Controlled Release, Dec. 2009